KidEmergencies.com - For Moms and Dads seeking more information on childhood emergencies and poisoningsiParenting Media Award December 3, 2008

Home
List of All Emergencies
About this Website
Other Resources
Free eLetter Sign Up
KidEmergencies.com - For Moms and Dads seeking more information on childhood emergencies and poisonings
Poison Links:

                          Bisphenol A (BPA)


What is Bisphenol A (BPA)?

Bisphenol A (BPA) is a chemical compound used to manufacture polycarbonate plastics.

Polycarbonate plastics are used as linings on many consumer products including:

·  
Sports bottles
·  
Baby bottles
·  
Food and drink containers
·  
Dental sealants
·  
Water cooler jugs
·  
Bicycle helmets
·  
Lining inside tin cans



How may my child be exposed to Bisphenol A?

  • Exposures can occur in the home because of the widespread use of polycarbonate plastics in household products.

  • Bisphenol A is typically bound in the polycarbonate plastic of these household products through strong chemical bonds, so we are unlikely to be exposed to Bisphenol A by simply handling plastic products. 

  • However, routine activities like heating liquids, storing acidic foods, and washing containers may create conditions where Bisphenol A may be released from a polycarbonate plastic. As a result, Bisphenol A may leach directly into food or drinks, resulting in exposure when the food or drinks are consumed.  
     
  • The amount of Bisphenol A that may leach into food and consumed is likely to be very small, but may occur frequently over a long period of time.  This is commonly referred to as a chronic exposure. 
     
  • Chronic exposures do not typically cause immediate adverse health effects.  Chronic exposures may, however, result in gradual changes in the body.  These changes may result in adverse health effects, particularly if exposures occur during a sensitive period of development, such as prenatal development or puberty.  
     

Biomonitoring (measuring levels of chemicals in the human body) by the Centers for Disease Control and Prevention shows that most Americans have detectable levels of Bisphenol A in their urine.



What health effects are associated with exposure to Bisphenol A?

  • Many health professionals are concerned about Bisphenol A exposure because it shares many chemical properties with hormones naturally found in the body.  These natural hormones regulate many body functions, including reproduction and normal cell growth, which may be disrupted by Bisphenol A. 

  • Effects of Bisphenol A as of this point have been demonstrated in animals, but not in humans, so whether or not this concern applies to human beings remains a point of disagreement among scientists.
It is difficult to draw conclusions from animal studies.  This is because the studies typically require exposing test subjects to high doses that may not be relevant and may use animals with body systems that are different than humans.

Health effects found in animals exposed to large amounts of BPA include:


Reproductive Effects

Animal research has shown that Bisphenol A is able to bind with estrogen receptors in the body. These estrogen receptors normally interact with the female hormone estrogen, which is involved in the regulation of normal sexual development.
 

As a result, Bisphenol A may be able to disrupt normal sexual development in girls and boys. Animal studies have shown that Bisphenol A exposure may lead to advanced onset of puberty and disruption of normal menstrual cycles in girls and decreased sperm production and quality in boys.   
 



Cancer

Some cancers that have been shown to be associated with Bisphenol A exposure in animal studies include: 

Breast, uterine and prostate cancer



How can I reduce my family’s exposure to Bisphenol A

  • Although there are limitations that make it difficult to definitively demonstrate that low-dose chronic exposures to Bisphenol A causes adverse health effects in people, there is evidence that exposure causes adverse effects in animals.  Therefore, it is prudent to minimize exposure to Bisphenol A whenever practical.

  • The Institute for Agriculture and Trade Policy’s Food and Health program has developed a fact sheet entitled “Smart Plastics Guide Healthier Food Uses of Plastics.” The fact sheet provides information on the health and safety of containers and recommendation to minimize exposure to chemicals in plastic. See http://www.agobservatory.org/library.cfm?refid=77083

  • The fact sheet includes a useful guide on the plastic labels found on some plastic household products.  There are currently 7 labels used on plastic products, which can be used to determine what chemicals are used in plastic products in your home.

  • Plastic containers with #1, #2, #4, or #5 labels are less likely to contain Bisphenol A and similar chemicals of concern, and are generally considered safer containers for storing food and liquids. 

  • Plastic containers with #3, #6, and #7 labels are more likely to contain Bisphenol A and other chemicals that may have similar health effects. 

  • You can reduce your family’s exposure to Bisphenol A by minimizing the use of #3, #6, and #7 plastic containers to store and heat food.  Brands that do not carry these include Born Free (which makes only BPA-free bottles), Gerber, Sassy, and Medela.

In addition, some practical tips you can do to reduce your family’s exposure when labeling information is not readily available include:

1. Use non-plastic containers to heat and store food

2. Replace older plastic containers that show sign of wear

3. Avoid the use of harsh detergents, which may increase Bisphenol A leaching, when washing plastic containers.




What should I do if I am concerned my child is being exposed to unsafe levels of Bisphenol A?

  • Unfortunately, there are limited tests that your physician can conduct to determine if you have been exposed to unsafe levels of Bisphenol A. 

  • The urine tests for phenols are limited because the test is only representative of exposures that occurred during one or two days prior to the test. 

  • These tests are also difficult for physicians to interpret because many substances may be metabolized in the body and converted into phenols, so it not clear the results indicate exposure to Bisphenol A or another substance that shares a common metabolic pathway in the body.




References

1.         vom Saal, S.M., and Hughes, C., An Extensive New Literature Concerning Low-Dose Effects of Bisphenol A Shows the Need for a New Risk Assessment. Environ Health Perspect 2005. v.113(8): p. 926–933.
2.         Kang J.H., K.K., Kondo F., Factors influencing the migration of bisphenol A from cans. J Food Prot, 2003. 66(8): p. 1444-7.
3.         Calafat, M., Kuklenyik, Z., Reidy, J.A., Caudill, S.P., Ekong, J., and Needham, L.L., Urinary Concentrations of Bisphenol A and 4-Nonylphenol in a Human Reference Population. Environ Health Perspect 2005. v.113(4): p. 391–395.
4.         Brotons JA, O.-S.M., Villalobos M, Pedraza V, Olea N, Xenoestrogens released from lacquer coatings in food cans. Environ Health Perspect, 1995. 103(6): p. 608-12.
5.         Kang JH, K.K., Kondo F, Factors influencing the migration of bisphenol A from cans. J Food Prot, 2003. 66(8): p. 1444-7.
6.         Maffini, M.V., Rubin, B.S., Sonnenschein, C., Soto, A.M., Endocrine disruptors and reproductive health: The case of bisphenol-A. Molecular and Cellular Endocrinology, 2006. 254-255: p. 179-186.
7.         Markey, C.M., Wadia, P.R., Rubin, B.S., Sonnenschein, C., Soto, A.M., Long-term effects of fetal exposure to low doses of the xenoestrogen bisphenol-A in the female mouse genital tract. Biol. Reprod., 2005. 72: p. 1344-1351.
8.         Smart Plastics Guide Healthier Food Uses of Plastics.  2005  [cited 2007 September, 25]; Available from:
http://www.agobservatory.org/library.cfm?refid=77083.

 

 

 

 

 

 

 

 

 

 

KidEmergencies.com - For Moms and Dads seeking more information on childhood emergencies and poisonings



About Dr. Marty

Signup for the
FREE Kid Emergencies Eletter:

Email
 
Most Common Emergencies - KidEmergencies.com
Asthma & Respiratory
Bites & Stings
Bones, Bruises, & Cuts
Crying Infant
Fever & Infections
Poisoning & Substance Abuse
Seizures
Belly Pain, Vomitting, Diarrhea, & Dehydration
Rashes
Other Emergencies

Pictures & MorePictures & More >>>

Poison Control Centers

KidEmergencies.com - For Moms and Dads seeking more information on childhood emergencies and poisonings

Emergency Checklist

PEMA

Quiz Time

This Month: Taken a fun, 8
question learning quiz on
Poisoning. Get started!